HPLC-UV-MS analysis of FOX-7 and ADN

Authors:

  • Holmgren Erik
  • Carlsson Håkan
  • Crescensi Carlo
  • Latypov Nikolaj
  • Goede Patrick

Publish date: 2004-01-01

Report number: FOI-R--1239--SE

Pages: 23

Written in: English

Abstract

Three different synthetic routes to FOX-7 are discussed and possible by-products are identified. The route starting from 2-methyl-pyrimidine-4,6-dione is the method currently used for production of FOX-7 on a pilot plant scale. Based on this route an HPLC-UV-MS method was developed for the analysis of FOX-7 its precursors and all major by-products. An HPLC-UV method has been developed for the analysis of dinitramide and the anionic impurities nitrate and nitrite in commercial ADN. All these anions could be analyzed on a porous graphitic carbon column.